GlaxoSmithKline Corporate Profile

GlaxoSmithKline
GlaxoSmithKline
980 Great West Road
Brentford, Middlesex TW8 9GS
United Kingdom
Phone: +44 (0)20 8047 5000
Website: www.gsk.com
We are a science-led global healthcare company with a mission: we want to help people to do more, feel better, live longer.

On 2 March 2015 we completed a 3-part transaction with Novartis which reshapes our business.

We acquired Novartis’s vaccines business (excluding influenza vaccines) and combined our Consumer Healthcare businesses to create a new company. By substantially strengthening Vaccines and Consumer Healthcare, we can deliver far-reaching benefits to patients and consumers, and further value to shareholders. In addition, Novartis acquired our marketed Oncology portfolio.

The vaccines, medicines and consumer healthcare products that we research and develop can improve people’s health and well-being, ultimately helping them to live life to its fullest and contribute to the prosperity of their communities.

Content

  • Genotoxic Impurities Part 2: Toxicological Overview

    This second article on genotoxic / mutagenic impurities (GTIs) will focus on toxicological aspects and discuss in more detail some of the themes mentioned in the first part of the series [1]. The current [2,3] and evolving guidance [4] is based on a number of key toxicological principles:

  • Genotoxic/Mutagenic Impurities Part 3: CMC (Chemistry, Manufacturing and Controls) Overview

    This third article in a series on genotoxic/mutagenic impurities (GTIs) will discuss the challenges facing synthetic and analytical chemists as they endeavor to identify and ultimately control levels of these GTIs or PGIs (potentially genotoxic impurities) in drug substance and drug products. ...

  • Analytical Methods and Control Strategies: The Forgotten Interface?

    There is considerable interest in enhancing approaches for analytical method development, validation, and lifecycle management which are aligned with Quality by Design (QbD) approaches to drug development. These enhanced approaches utilize risk assessments and in-depth systematic evaluations ...

  • Solubility in Pharmaceutical R&D: Predictions and Reality

    Lipinski’s seminal paper on experimental and computational (in silico) methods to estimate the solubility and permeability of drug candidates was published in 1997. The iconic “Rule of 5” predicted that absorption was adversely impacted when the calculated LogP (cLogP) was >5, when molecular ...
GlaxoSmithKline
GlaxoSmithKline
980 Great West Road
Brentford, Middlesex TW8 9GS
United Kingdom
Phone: +44 (0)20 8047 5000
Website: www.gsk.com

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