DiCE Molecules announced a multi-year collaboration to discover new small molecules against multiple targets of interest to Genentech. The collaboration will build upon DiCE’s unique technology platform, which leverages the power of directed chemical evolution to select and optimize low molecular weight compounds against important pharmaceutical targets such as protein-protein interfaces.
“Genentech is a recognized leader in biotechnology innovation, including in small molecule research and development,” said Kevin Judice, President and Chief Executive Officer of DiCE. “We are incredibly pleased to work with Genentech and believe this collaboration speaks to the potential of our technology to address previously intractable, but very important targets with novel chemical matter.”
The collaboration focused on small-molecule discovery and development encompasses multiple targets.
Under the terms of the agreement, DiCE will receive an undisclosed upfront payment and is eligible to receive research, development, regulatory, and commercial milestone payments based upon achievement of certain pre-determined milestones. Full financial terms have not been disclosed.
“DiCE’s unique technology naturally complements Genentech’s efforts in small molecule drug discovery and offers the potential to unlock some of the most challenging targets, including those that were once thought to be undruggable,” said James Sabry, Senior Vice President and Global Head of Genentech Partnering.