Sinovant Sciences and Renexxion announced the initiation of a collaboration to pursue the development of naronapride, an investigational gastrointestinal prokinetic, in Greater China. As part of the collaboration, Renexxion has granted Sinovant an exclusive license for the development and commercialization of naronapride in China, Hong Kong, Macau, and Taiwan. Deal terms include license fee payments, commercial milestones, and tiered royalties.
Sinovant intends to initially develop naronapride in irritable bowel syndrome with constipation (IBS-C), a condition that impacts approximately 13 million individuals in China and for which few efficacious treatments are currently available. Sinovant also plans to expand development into other gastrointestinal disorders.
"Gastrointestinal conditions represent a significant unmet medical need in China, and we believe that naronapride is a promising therapy with a clinically validated mechanism of action," said Canwen Jiang, MD, PhD, Chief Executive Officer of Sinovant Sciences."