Nemus Bioscience announced an agreement with AMRI for the development and manufacture of Nemus’ proprietary cannabinoid-based active pharmaceutical ingredients (API). The agreement will utilize AMRI’s process chemistry expertise in the synthesis and formulation of Nemus’ proprietary prodrug of tetrahydrocannabinol (THC). This molecule forms the basis of NB1111, Nemus’ compound in development for the treatment of glaucoma.
“Advancing our lead therapeutic candidates into the API manufacturing stage is a major milestone for our company and is pivotal for initiating human studies,” said Brian Murphy, M.D., CEO-CMO of Nemus. “Cannabinoid-based therapies have the potential to revolutionize glaucoma therapy by not only lowering intraocular pressure, but by exerting a direct neuroprotective effect on the cells of the optic nerve, thereby preserving vision.”
“AMRI looks forward to working with Nemus to bring this new class of cannabinoid-based therapies through the developmental process,” said Christopher Conway, Senior Vice President of Discovery, Development and Analytical Services at AMRI. “AMRI will focus on manufacturing synthetic versions of Nemus’ proprietary prodrug of THC at our U.S. Drug Enforcement Administration (DEA) approved facilities.”