Dr. Jonathan Goldman, CEO, announced that Abzena has augmented existing 500 L scale biologics equipment with 20m$ of investment into two new manufacturing suites at 500 L and 2000 L scale in a new GMP facility in San Diego, which will be equipped with Sartorius single use bioreactors. Abzena’s existing expertise in cell line development is strengthened with a new ambr 15 automated high throughput bioreactor in Cambridge, UK, and existing synthetic chemistry capacity is increased with build out of a fully equipped multifume hood laboratory in Bristol, Pennsylvania.
“Sponsors have noted our unique single source high quality integrated solution for biotherapeutics and Antibody Drug Conjugates (ADC) ranging from discovery to phase II scale under GMP,” Dr. Goldman said. “They wish to maintain excellent scientific quality, have a single point of contact and avoid risks of tech transfer. We have received many requests to support programs to phase II and beyond. We will continue to deliver industry-leading drug discovery, development and manufacturing services from our world-class, fully-integrated sites in the US and UK.”
Dr. Goldman explained that Abzena’s antibody Drug Substance manufacturing solution will be built in two new suites housed in the facility recently opened by Abzena in San Diego. These will contain new Sartorius 500 L and 2000 L single use bioreactors supported by a comprehensive range of scale up and process development equipment. The service will be further complemented by additional cell line development and chemistry capacity.
“Our company is experiencing significant demand for biologics, ADC constructs and other complex small molecules [or APIs]. We are delighted to commit approximately 20m$ to initiate these improvements which will start to become available to customers during 2019,” Dr. Goldman said.