Logan Instruments has officially launched their Permeation-Barrier Membrane (PB-M) into international markets. PB-M is a cellulose membrane. This model has similar acidity to human epidermis which allows the transfer of novel drugs. Measurements with the barrier are easy, fast, and reproducible. Each PB-M’s diameter is 25 mm when packed in a 5-cavity plate. The membranes need to avoid sun light exposure and UV radiation. They expire after 2 years.
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Logan’s PB-M can better simulate the in-vitro drug permeation through human skin. It is also non-toxic and harmless to the human body and is systematically produced to ensure the consistency of the product. Additionally, its serum-free feature is more convenient for storage and transportation. The PB-M has a similar permeation rate to human skin, allowing for more accurate test results.
PB-M is more stable for IVPT/IVRT tests as tests performed using PB-M show less variation compared to other membrane manufacturers.