WILMINGTON, Mass. & MONTREAL--(BUSINESS WIRE)--Apr. 6, 2021-- Charles River Laboratories International, Inc. (NYSE: CRL) and Valence Discovery today announced the formation of a strategic partnership to provide clients access to Valence’s artificial intelligence platform for molecular property prediction, generative chemistry, and multiparameter optimization.
Building on research done by Valence’s founding team at Mila, the world’s largest deep learning research institute, the Valence platform enables the design of small molecule drug candidates in novel regions of chemical space, followed by rapid optimization against project-specific potency, selectivity, safety, and pharmacology criteria. Valence has pioneered the application of few-shot learning in drug design, allowing the company to unlock prediction tasks for which only small amounts of training data are available, overcoming a critical limitation of existing machine learning technologies in drug discovery.
Partnering to Accelerate Discoveries
By combining best-in-class machine learning technologies with Charles River’s end-to-end capabilities, the alliance has the potential to significantly accelerate discovery efforts from hit design through lead optimization.
Through the collaboration, Charles River clients will have the option to access Valence’s platform to support their drug discovery efforts. When taking advantage of this option, clients can expect increased diversity in chemical matter being investigated, in combination with more rapid optimization against complex, project-specific design criteria, ultimately reducing timelines and improving success rates for drug discovery projects.
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