Piramal Pharma Solutions has expanded its peptide API facility in Turbhe, India, with a new spray drying suite designed to support challenging formulations for peptides, HPAPIs and other biomolecules. The company said the suite adds Band 5 containment capacity and is equipped with its own air handling units, nitrogen supply and control systems.[
The new suite is intended for small-volume, high-potency batches and operates as a closed-loop system with advanced safety features, including specialized HVAC, airlocked entries and exits, operator isolation and a dedicated cleaning area. Piramal said the processing area meets ISO Class 8 cleanliness standards to help maintain control over the manufacturing environment.
Spray drying converts liquid formulations into dry powders in a single step, which can improve bioavailability, tighten particle-size control and help preserve sensitive compounds. The company said the technique is especially important for peptides, which can be unstable at high temperatures and often require strict control over particle properties. The new suite can handle highly concentrated solutions with up to 30% water content and has a feed rate of up to 1 liter per hour.
Piramal Pharma Solutions said the new capability strengthens its peptide development and manufacturing offering and supports growing demand for innovative molecules. Dr. Jordi Bacardit, global technical lead on peptides at PPS, said spray drying allows tight control over temperature and solvent environment and helps bring stable, high-quality peptide formulations to patients worldwide.