Pharmaceutical Dissolution Testing Products and Services

Dissolution testing allows for the examination and prediction of the in-vitro behavior of pharmaceutical formulations. Drug release behavior of pre-formulations is made possible by the use of specialized dissolution equipment. By dissolution testing, a researcher can simulate the behavior of capsule, bead, and enteric-coated tablets in-vitro.

Important Applications of Dissolution Testing

• Quality Control
• Replicating certain mechanisms of in-vitro drug release
• Determining if drug behavior meets regulatory standards
• Dissolution simulation when choosing pharmaceutical excipients

Examples of Pharmaceutical Dissolution Equipment

Paddle apparatus dissolution testing is used to simulate tablet behavior in the gastrointestinal tract. The release behavior of implants and transdermal medications can also be tested with dissolution equipment. The reciprocating cylinder dissolution apparatus ("Bio-Dis") is excellent for examining the dissolution behavior of extended release products. Dissolution analysis is key in determining the homogeneity of the final pharmaceutical product. Whether controlled by the bench user or fully automated, the implementation of a dissolution testing protocol is crucial in the final stages of drug development to ensure the efficacy, safety, and marketability of the final compound.