limentiv Inc., AcelaBio Inc., and PharmaNest Inc. announced their collaborative effort aimed at revolutionizing precision medicine and artificial intelligence (AI)-enabled digital pathology solutions for metabolic dysfunction-associated steatohepatitis (MASH), previously known as nonalcoholic steatohepatitis (NASH) clinical trials. This collaboration will enable clinical trial sponsors to quantify the histological effects of compounds and gain deeper insight into underlying mechanisms in MASH-targeted therapies using state-of-the-art spatial transcriptomics and AI-powered single-fiber and single-cell digital pathology. By harnessing the collective expertise of Alimentiv, AcelaBio, and PharmaNest, this collaboration will establish an integrated ecosystem that seamlessly combines high throughput specialty anatomic and molecular pathology, precision medicine technologies, bioinformatics, and AI-powered digital pathology image analysis. Integrating these cutting-edge solutions is a significant advancement in applying novel technologies to enable high-quality end-to-end tissue assays, allowing clinical trial sponsors to drive scientific discoveries and accelerate drug development in MASH, a disease with a growing impact and currently no approved therapies.
The collaborative efforts of Alimentiv, AcelaBio, and PharmaNest will facilitate the seamless integration of robust digital pathology operational workflows and Artificial Intelligence in MASH clinical trials, ultimately leading to the development of personalized therapies and improving patient outcomes.
PharmaNest, recognized for its excellence in MASH digital pathology and Artificial Intelligence analysis services, will play a pivotal role in this collaboration by providing high-resolution, single-fiber, and single-cell quantitative image analysis and AI-powered biomarkers from the same images reviewed by pathologists for critical endpoint assessments. Together, these organizations will enhance the quality of current histological endpoints required for the interim FDA approval of therapies in MASH and enable the analysis of complex data sets, leading to a comprehensive understanding of MASH pathology and the discovery of new biomarkers.
The partnership with Alimentiv and AcelaBio will ensure sponsors receive a superb end-to-end digital pathology tissue assay where pre-analytical conditions are well controlled during the length of a study.
The collaboration between Alimentiv, AcelaBio, and PharmaNest represents a substantial leap forward in integrating precision medicine and digital pathology solutions for MASH clinical trials. By uniting their expertise, these organizations aim to further enhance early drug development efficiency to get safe and effective treatments to patients in a more expedient fashion.
Subscribe to our e-Newsletters
Stay up to date with the latest news, articles, and events. Plus, get special
offers from Pharmaceutical Outsourcing – all delivered right to your inbox! Sign up now!