This white paper describes the use of PVA-based Parteck® SRP 80, a functional excipient specifically developed for matrix-based sustained release oral solid dose formulations. With a mean particle size of 80 µm, Parteck® SRP 80 excipient is a PVA optimized for drug dissolution, easy handling, good flowability and good reproducibility with respect to both sustained API release and direct compression (DC) manufacturability. Batch-to-batch consistency ensures consistent quality and enables use of QbD to further minimize risks in development and manufacture. Parteck® SRP 80 excipient is also compliant with Ph. Eur., USP, ChP and JPE monographs.
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