Our comprehensive suite of bioassay solutions includes both established assays and custom assay development matched to your individual program needs.
Our bioassay services include:
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Target validation
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Hittolead screening
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Antibody Design & Development
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Specificity & tissue profiling
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Mode of action
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Immunogenicity & Safety assessment
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Biologics Manufacturing Potency & Batch Release
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Manufacturing – Potency & Batch release
What sets Abzena's bioassay and analytical development services apart?
- Stateoftheart laboratories with an extensive range of biophysical equipment and capabilities
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Extensive experience in supporting manufacturability, developability assessment, and lead candidate selection for a wide range of modalities including mAbs, bispecifics, and bioconjugates
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Expertise in protein characterization and proteomics provide an indepth molecular understanding, including identification of posttranslational modifications and degradation sites
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Analytical capabilities to support bioconjugate programs including DAR and conjugation site identification as well as serum stability and payload release studies and free payload analysis
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Analytical capabilities to support CLD programs, including determination of critical or product quality attributes and reference standard characterization
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Significant immunoproteomics expertise supports the derisking of potential immunogenicity of biotherapeutics and or to enhance vaccine development
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We offer a full range of phase appropriate solutions, from simple bioassays with high accuracy and precision to complex coculture primary cell models for mode of action studies
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Comprehensive suite of functional bioassays with over 30 offtheshelf assays, as well as tailored solutions to answer specific questions that offtheshelf assays may not be able to answer
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Investigative approach to provide data early in the development process allowing informed decision making on whether to progress or kill a program, translating to significant time/cost savings
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Extensive experience with a wide range of modalities, including mAbs, ADCs, AOCs, bispecifics and immunomodulators