Leucid Bio and Lonza Collaborate to Leverage the Cocoon Platform for Automated Manufacturing of Personalized CAR T-Cells

Leucid Bio a biotech company pioneering next-generation cell therapies for hard-to-treat cancers, today announces that it has entered a strategic collaboration with Lonza to utilize Lonza's Cocoon® Platform for the Company's forthcoming Phase I clinical trial, through to commercial manufacturing.

Under the terms of the collaboration, Leucid will utilize Lonza as its preferred manufacturer, aiming to deliver high quality cell therapies quickly and cost-effectively to patients in a decentralized manufacturing model. Leucid is, in turn, one of Lonza's preferred collaborators on the Cocoon® Platform, and both companies will work together to optimize and streamline the manufacturing process for Leucid's CAR-T therapies. As a preferred collaborator, Leucid will have early access to new Cocoon® Platform technologies.

Founded to translate 20 years of pioneering CAR-T research led by Dr John Maher at King's College London, Leucid has developed a proprietary engine that builds upon Dr Maher's novel parallel CAR-T model which positions these molecules in a more natural biological configuration. The Company's technology confers properties on the CART-cells that enable them to consistently outperform previous generations of CAR-T therapies in pre-clinical studies. As a result, this leads to enhanced T-cell potency and persistent long-term response with reduced toxicity.

Artin Moussavi, Chief Executive Officer of Leucid Bio, said: "Following on from our successful Series A financing, we are delighted to be working with Lonza and its Cocoon® Platform. This agreement will allow us to accelerate our path to the clinic, treating more patients sooner, potentially at point-of-care, and help to solve the key issues facing CAR-T therapeutics."

John Maher, Chief Scientific Officer of Leucid Bio, added: "This is a fantastic opportunity to collaborate with Lonza, enabling us to develop a state-of-the-art scalable manufacturing process. This will significantly help Leucid to efficiently transition our CAR-T pipeline for maximum patient benefit."

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