Latest Articles

  • Executive Q&A - A Strategic Acquisition: Insights and Ideas

    An interview with Brian Morrissey, General Manager of Gaelic Laboratories, which has acquired Athlone Laboratories in a strategic deal that typifies the current pharma M&A landscape and puts all of Ireland’s Beta-Lactam manufacturing capacity under one ownership umbrella. read more

  • Sustaining the Future of Life Science Product Research

    Few people say it outright, but the integrity of stored research and clinical samples underpins all scientific and medical progress. Every breakthrough drug, advanced therapy, or medical device depends on millions of biological, chemical, and physical samples that must be preserved intact across the entire product lifecycle. read more

  • A Critical Inflexion Point: The Indisputable Case for Next-Gen Pharmacovigilance

    Adverse event case processing is an enormous cost center and compliance issue for life sciences. As revenues stagnate for many pharma companies and profits come under new pressures, the expectation to improve its operational efficiency is substantial. But that cannot be at the expense of quality, or patient safety – the very purpose of pharmacovigilance. Organizations and their PV service providers have no choice but to take a smarter approach, underpinned by artificial intelligence and advanced automation. The cost and risk management benefits are clear, while the wider gains will include a more proactive PV operation, says Qinecsa’s John Cogan. read more

  • An ADME Guide for Successful siRNA Therapeutics: Insights from Approved Drugs

    Small interfering RNA (siRNA) therapeutics have emerged as a trans formative class of drugs, offering targeted gene silencing capabilities that hold promise for treating various diseases. Since the landmark approval of the first siRNA drug Patisiran in 2018, the therapeutic siRNA landscape has expanded significantly, with multiple drugs, including Givosiran, Lumasiran, Inclisiran, and Vutrisiran, now approved in both the US and EU markets. Understanding these drugs’ absorption, distribution, metabolism, and excretion (ADME) characteristics is critical for optimizing their development and clinical application of siRNA therapeutics. read more